Grant and Award Recipients 2004

OREF continues to support quality orthopaedic research through grants and awards totaling $3.4 million from the Fund of 2003.  Additionally, $1,964,000 was raised for use by various specialty societies. Congratulations to the following grantees and award winners approved by the OREF Board of Trustees:

Clinician-Scientist Awards
Career Development Awards
Research Grants
Prospective Clinical Research Grants
Resident Research Awards
OREF Clinical Research Award
Fellowship in Health Services Research
Zimmer Orthopaedic Career Development Award
Sponsored Research
Educational Awards
Journal of Bone and Joint Surgery Resident Journal Club Grants
Fred W. Hark, M.D. and William A. Hark, M.D. Lectureship Awards
Patel Traveling Fellowship
State Orthopaedic Society Lectureships
Medical Student Summer Orthopaedic Research Fellowship


Clinician-Scientist Awards

This award is intended to encourage young orthopaedic surgeons to pursue a career as a clinician-scientist. Three-year awards of $100,000 per year were awarded to three candidates.

RECIPIENT PROJECT
David L. Glaser, M.D.
University of Pennsylvania
Funded by the Dr. Zachary B. and Mrs. Kathleen Friedenberg Endowment Fund
The Origin of Cells Within Post-Natal Musculoskeletal Tissue Formation and Repair
Javad Parvizi, M.D.
Rothman Institute at Thomas Jefferson University
Funded by the Journal of Bone and Joint Surgery
Smart Orthopaedic Implants with Modified Biological Surfaces
James R. Slauterbeck, M.D.
Texas Tech University Health Sciences Center
Funded by the Dr. Dane and Mrs. Mary Louise Miller Endowment Fund
Gender Effects on Anterior Cruciate Ligament Remodeling

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Career Development Awards

Award encourages a commitment to scientific research in orthopaedic surgery. Awards of up to $75,000 per year for three years were awarded.

RECIPIENT PROJECT
John C. Clohisy, M.D.
Washington University
The Molecular Role of RANKL in Implant Particle-Induced Osteolysis
Harry K.W. Kim, M.D.
Shriners Hospitals for Children, Tampa
Recipient of the Thomas M. Coffman Career Development Award
Effects of Aging on Angiogenesis in the Repair of Ischemic Necrosis of the Femoral Head

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Research Grants

Grants encourage new investigators by providing seed money and start-up funding of up to $50,000 per year for up to two years. Nine grants were funded.

RECIPIENT PROJECT
Elie F. Berbari, M.D.
Mayo Clinic
Dental and Other Invasive Procedures and the Risk of Prosthetic Joint Infection: A Hospital Based Control Study
Jennette L. Boakes, M.D.
Shriners Hospital for Children, Sacramento
Vastus Lateralis Muscle Adaptation During Limb Lengthening
Craig D. Brigham, M.D.
O.L. Miller Research Institute
Accuracy and Reproducibility of Cervical Spine Radiographs Using Radio-Opaque Rulers Compared to Cervical CT Scans
Lee D. Kaplan, M.D.
University of Wisconsin, Madison
Development of Partial Thickness Articular Cartilage Injury in an Ovine Model
Young W. Kwon, M.D., Ph.D.
NYU-Hospital for Joint Diseases Medical Education and Research Institute of Colorado
Effects of Angiogenic Factors on an Experimental Animal Model of Osteonecrosis Patellofemoral Pain
Francis Y. Lee, M.D., Ph.D.
Columbia University
Stromal Cell Derived Factor-1 (SDF-1) Regulation of Tumor-Induced Osteolysis
Orhum K. Muratoglu, Ph.D.
Massachusetts General Hospital
Crosslinked UHMWPE with High Fatigue Resistance Using High Pressure Crystallization
Christopher L. Peters, M.D.
University of Utah
Comparative Stress Analysis of Hip Dysplasia
Wei Zhu, Ph.D.
Hospital for Special Surgery
Funded by the Musculoskeletal Transplant Foundation
BMP2/7 Heterodimer Regulates Osteoblastic Differentiation in Human Bone Cells

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Prospective Clinical Research Grants

These grants provide funding for promising prospective clinical research projects. Two awards of up to $50,000 per year for up to three years were awarded.

RECIPIENT PROJECT
Weiping Ren, M.D., Ph.D.
Wayne State University
Erythromycin: A Cure for Aseptic Loosening?
John G. Thometz, M.D.
Medical College of Wisconsin
Functional Evaluation of Post Surgical Clubfoot: Based Upon Existing Clinical Assessment Scores and Foot Motion Analysis

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Resident Research Awards

Award is to encourage development of research interests for residents and orthopaedic fellows in approved orthopaedic programs. Grants of $15,000 are offered to be used over a 12-month timeframe.

Carl A. Deirmengian, M.D.
Children's Hospital of Philadelphia
Leukocyte Expression Signatures in Acute Pediatric Arthritis: A Novel Approach for Diagnosis
Sanjeev Kakar, M.D.
Boston University
Recipient of the Marshall F. Urist Residency Research Award
Funded by the Association of Bone and Joint Surgeons
Molecular Mechanisms of PTH-Mediated Enhancement of Fracture Repair
Eric O. Klineberg, M.D.
Veterans Administration Hospital, Puget Sound
Recipient of the Charles H. Herndon Residency Research Award
Funded by the Musculoskeletal Transplant Foundation
Splicing Factors Effect Chondrocyte Differentiation and Collagen Synthesis
Jonathan H. Lee, M.D.
Columbia University
Role of Subchondral Bone in Osteoarthritis
Brian M. Leo, M.D.
University of Virginia
Regional Gene Therapy in GDF-5 Deficient Mouse Intervertebral Disc
Anthony V. Mollano, M.D.
University of Iowa
Recipient of the Katherine Wolcott Walker Resident Research Award
Role of Tumor Suppressors in Chondrocyte Aging
Greg M. Osgood, M.D.
Columbia University
A Prospective Randomized Study of Teriparatide on Proximal Humerus Fracture Healing in Patients with Osteoporosis
Michael W. Peelle, M.D.
Washington University
Localization and Identification of the Gene Involved in Autosomal Dominant Congenital Vertical Talus
James A. Ryan, M.D.
University of California - Davis
Recipient of the Charles H. Herndon Residency Research Award
Funded by the Musculoskeletal Transplant Foundation
Combined Effects of Osteogenic Protein-1 and Insulin-like Growth Factor-1 on Articular Cartilage Repair in an In Vivo Rabbit Model of Osteochondral Injury
Andrew N. Swanson, M.D.
Hospital for Special Surgery
Neurotization Versus Standard Nerve Repair: Comparison of Surgical Technique in an Animal Model of Chronically Denervated Muscle
Debra J. Thomas, M.D.
Dorr Arthritis Institute/King-Drew Medical Center
Recipient of the Centerpulse Resident Award for Minimally Invasive Surgery
Funded by Centerpulse Orthopaedics
Psychological and Physiological Aspects of "Minimally Invasive" Total Hip Replacement Surgery
Andrew J. L. Walsh, Ph.D.
University of California, San Francisco
Mesenchymal Stem Cell Therapy for Intervertebral Disc Regeneration

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OREF Clinical Research Award

This award recognizes outstanding clinical research related to musculoskeletal disease or injury. One award of $20,000 was awarded.

RECIPIENT PROJECT
Frank R. Noyes, M.D.
Edward Grood, Ph.D.
Thomas Andriacchi, Ph.D.
Sue Barber-Westin, B.S.
Deaconess Hospital, Cincinnati
Factors Affecting the Treatment of Anterior Cruciate Ligament-Deficient Knees with Lower Limb Malalignment and Associated Ligamentous Instabilities: A Correlated, Clinical, Biomechanical, and Dynamic Gait Analysis

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Fellowship in Health Services Research

Funding develops orthopaedic surgeons with research skills to undertake and manage health services and outcomes research. One two-year fellowship is offered annually at $70,000 per year.

RECIPIENT  
Judith F. Baumhauer, M.D.
University of Rochester
 

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Zimmer Orthopaedic Career Development Awards

This award promotes the advancement of scientific and/or clinical training of new orthopaedic surgeons who have a clinical or scientific interest in total joint surgery and/or trauma treatment. The qualified candidate must be an orthopaedic surgeon who is currently completing or has completed formal training within the past four years. The amount of the award is up to $50,000 for up to one year.

RECIPIENT PROJECT
Michael T. Archdeacon, M.D.
University of Cincinnati Medical Center
Prospective Functional Performance Evaluation of Lower Extremity Biomechanics After Femur Fracture Treated with Intramedullary Nailing
Michael P. Bolognesi, M.D.
University of Utah Medical Center
The Effect of COX-2 Inhibitors on Bone Ingrowth in Porous Coated Titanium Implants in Humans
Alejandro Gonzalez Della Valle, M.D.
Hospital for Special Surgery
The Utility and Precision of Standard and Computerized Pre-operative Planning for Primary Total Hip Arthroplasty
Ginger E. Holt, M.D.
Vanderbilt University Medical Center
An In Vivo Bioreactor: Unraveling Tumor / Host Environment Interactions Using a Vascularized Coral Template
Henry C. Sagi, M.D.
Florida Orthopaedic Institute
Indomethacin and Prevention of Heterotopic Ossification in Acetabular Fractures

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Sponsored Research
RECIPIENT PROJECT
Clifford W. Colwell, M.D.
Scripps Clinic
Funded by Aventis Pharmaceuticals
Prevalence of Coagulation Factors and Mutations in Predicting Venous Thrombosis in Patients Undergoing Total Joint Replacement

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Educational Awards

Awards provide one time of funding of up to $25,000 for educational programs developed in conjunction with a recognized, national organization: to evaluate the effectiveness of orthopaedic education at all levels; clinical consensus conferences, workshops and symposia; research and development of educational electronic media; and innovative approaches to education. Nine programs were funded.

RECIPIENT PROJECT
American Academy of Orthopaedic Surgeons Workshop: Influence of Sex and Gender on Musculoskeletal Health
American Orthopaedic Association Clinician Scientist: Business Aspects
American Orthopaedic Association International Center for Orthopaedic Education
Brigham and Women's Hospital 3rd International Meeting on Gene Therapy in Rheumatology and Orthopaedics
Gordon Research Conference 12th Gordon Research Conference on Musculoskeletal Biology and Bioengineering: Orthopaedic Tissue Engineering: Basic Science to Clinical Application
Indiana University 34th Sun Valley Workshop on Skeletal Biology
Journal of Bone and Joint Surgery Web-Based Enhancements of Peer-Reviewed Articles
Massachusetts General Hospital Development of a Computerized Orthopaedic Pathophysiologic Teaching System for Residents and Staff Based on the Jaffe, Erdheim and Campbell Collections (JEC Collection)
Orthopaedics Overseas OREF-OO Travel, Fellowship

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Journal of Bone and Joint Surgery Resident Journal Club Grants

The objective of this program is to support journal club activities for orthopaedic residents. Participation in this program is open to existing and new journal clubs. The program enhances residency training by providing educational information on managing an effective journal club, and teaches residents how to evaluate current scientific literature, grants of $2,500 per program were awarded.

RECIPIENTS (2003)
Akron General Medical Center Summa Health System, Akron
Barnes-Jewish Hospital/Washington University State University of New York at Buffalo
Boston University Medical Center SUNY Upstate Medical University
Brooke Army Medical Center Temple University Hospital
Cleveland Clinic Foundation Texas Tech University
Columbia-Presbyterian Medical Center UMDNJ - Robert Wood Johnson Medical School
Creighton - Nebraska Health Foundation University Hospitals of Cleveland
Duke University Medical Center University of Alabama at Birmingham
Geisinger Medical Center University of Florida HSC/Jacksonville
Greenville Hospital System University of Kansas - Wichita
Johns Hopkins University Hospital University of Maryland
Louisiana State University - Shreveport University of New Mexico
Madigan Army Medical Center University of North Carolina
Maimonides Medical Center University of South Carolina
Massachusetts General / Harvard University of Tennessee - Campbell Clinic
McLaren Regional Medical Center University of Tennessee - Chattanooga
Medical College of Ohio University of Washington
Naval Medical Center - San Diego University of Wisconsin
San Francisco Orthopedic Residency Program Walter Reed Army Medical Center
SAUSHEC at Wilford Hall Medical Center William Beaumont Hospital
RECIPIENTS (2004)
Albany Medical Center Brooke Army Medical Center
Drexel University Duke University
Dwight D. Eisenhower Army Medical Center Hamot Medical Center, Erie, PA
Henry Ford Health Systems, Detroit, MI Johns Hopkins University
Keller Army Community Hospital, West Point Maimonides Medical Center, Brooklyn
Medical University of South Carolina Mount Carmel Medical Center, Columbus, OH
Northwestern University Oregon Health & Science University
Rush University Medical Center SAUSHEC, Wilford Hall Medical Center
Summa Health System, Akron SUNY at Buffalo
Texas Tech Health Sciences Center Tripler Army Medical Center
University of Chicago University of Florida, Gainesville
University of Iowa Hospitals and Clinics University of Minnesota
University of North Carolina University of Pennsylvania
University of Rochester Walter Reed Army Medical Center
Wayne State University William Beaumont Army Medical Center

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Fred W. Hark, M.D. and William A. Hark, M.D. Lectureship Awards

Award provides up to $2,500 for a lecture on a topic of interest to orthopaedic surgeons. Six awards were funded.

RECIPIENT
Brooke Army Medical Center University of Illinois at Chicago
Children's Memorial Hospital University of Minnesota
Dartmouth College University of Pennsylvania
Duke University University of Vermont
Eastern Orthopaedic Association University of Washington
Medical College of Ohio University of Wisconsin - Madison

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Patel Traveling Fellowship

Grant provides funding for a young orthopaedic surgeon from India to travel to the U.S. for specialty training, including attendance at an appropiate AAOS course.

RECIPIENT
Kalpesh M. Trivedi, M.S. (Ortho)
Ahmedabad, India

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State Orthopaedic Society Lectureships

Award provides an honoraria of $1,000 for speakers at state and reginol society annual meetings.

Arizona Orthopaedic Society Mid-Central States Orthopaedic Society
Arkansas Orthopaedic Society Mississippi Orthopaedic Society
California Orthopaedic Association Missouri State Orthopaedic Society
Clinical Orthopaedic Society New Jersey Orthopaedic Society
Connecticut Orthopedic Society North Carolina Orthopaedic Association
Eastern Orthopaedic Association Ohio Orthopaedic Society
Florida Orthopaedic Society Pennsylvania Orthopaedic Society
Georgia Orthopaedic Society Rhode Island Orthopaedic Society
Tennessee Orthopaedic Society
Hawaii Orthopaedic Association
Indiana Orthopaedic Society Texas Orthopaedic Association
Iowa Orthopaedic Society Vermont Orthopaedic Society
Kansas Orthopaedic Society Virginia Orthopaedic Society
Louisiana Orthopaedic Association Washington Orthopaedic Society
Maryland Orthopaedic Association Washington State Orthopaedic Association
Massachusetts Orthopaedic Association Western Orthopaedic Association
Michigan Orthopaedic Society Wisconsin Orthopaedic Society
Mid-American Orthopaedic Association

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Medical Student Summer Orthopaedic Research Fellowship

The goal of this program is to encourage medical students with an interest in pursuing a career in orthopaedics. Ten awards of $2,500 each were awarded in 2004.

RECIPIENT  
Jessica M. Belz Children's Hospital of Philadelphia
Paul K. Edwards University of Arkansas for Medical Sciences
Nicole L. Fetter Duke University
Robert R.L. Gray Brown Medical School
Casey Jo Humbyrd Harvard Medical School
Michael Z. Koontz University of California, Irvine
Erik R. Lovria University of Rochester School of Medicine and Dentistry
Mollie O. Manley Case Western Reserve University
Lisa N. Rapoport University of California, San Francisco
John N. Thomas III Rothman Institute at Thomas Jefferson University

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