Patient care applications:

ARTHRITIS

Howard S. An, MD
More accurate diagnosis and more selective, lower-risk treatments for patients suffering from low back pain due to disc degeneration or arthritis

Carl T. Brighton, MD, PhD
Electrobiological therapies that provide alternative treatments for osteoarthritis patients and patients whose fractures won't heal

Joseph A. Buckwalter, MD
New approaches for repairing joint surfaces to lessen arthritis pain

Victor M. Goldberg, MD
Development of specific therapies to care for and lessen pain of arthritis

Jennifer M. Wolf, MD
Treatments that may prevent thumb carpometacarpal arthritis, especially in women, by blocking relaxin hormone receptors

Patient care applications:

BONE, CARTILAGE, TENDON, NERVE and MUSCLE

Joseph A. Abboud, MD
Lessening the extent of tendon disease or damage for patients with hypercholesterolemia

Jaimo Ahn, MD, PhD
Development of small-molecule inhibitors to reduce the effect of BMP regulators and increase the rate of bone healing

Hani A. Awad, PhD
Allografts that reduce scarring and restore gliding and function of repaired flexor tendons

Nicole S. Belkin, MD
Implants to treat cartilage pathology

David B. Burr, MD
Exercise programs that prevent osteoporotic fractures

Laurence E. Dahners, MD
Demonstrated that braces that allow controlled motion of ligaments resulted in faster, stronger healing

David R. Diduch, MD
Method to determine if new techniques involving cells to influence cartilage healing are effective, ensuring patients receive the best possible treatment for cartilage injuries

William F. Enneking, MD
Establishment of the principles for bone banks that provide bone for procedures such as fusions

William H. Harris, MD
Osteoporosis treatments that reduce fractures or other injuries

MaCalus V. Hogan, MD
Development of tissue engineering therapies to heal, repair and regenerate acute or chronically injured tendons

Xuhui Liu, MD
Decreased muscle atrophy after injury, immobilization or surgery

Frederick (Rick) A. Matsen III, MD
Assessment of limbs at risk for compartmental syndrome

Wen-Ning Qi, MD
Better treatments for peripheral nerve injury by suppressing calcium channels or rebalancing nitric oxide products 

Stavros Thomopoulos, PhD
Employing biofactors to improve clinical outcomes of tendon-to-bone healing

Stephen B. Trippel, MD
Growth factors that interact with one another and can be used to treat patients with skeletal growth deficiencies

Marshall R. Urist, MD
The development and advancement of Bone Morphogenetic Protein to encourage faster healing, stronger fusions, and longer-lasting joint replacement

Michael J. Yaszemski, MD, PhD
Bone graft materials that could be used to target holes left by disease or injury, where bone reconstitution is difficult to achieve

Patient care applications:

COMBAT ZONE

Carl T. Brighton, MD, PhD
Electrobiological therapies that provide alternative treatments for osteoarthritis patients and patients whose fractures won't heal

Lt. Col. Steven J. Svoboda, MD, USMC
Early detection and treatment of joint degeneration for patients likely to develop osteoarthritis after ACL reconstruction

Michael J. Yaszemski, MD, PhD
Bone graft materials that could be used to target holes left by disease or injury, where bone reconstitution is difficult to achieve

Patient care applications:

EDUCATING NEW INVESTIGATORS

Grant Writing
Hands-on workshops for writing National Institutes of Health-caliber grants

Lectureships
Funding for lectureships on topics ranging from diagnostic strategies to legal perspectives on liability reform to practice management and medical legal issues

Henry J. Mankin, MD
A searchable database that contains the pathology of bone, cartilage, and soft tissue diseases and provides information to make better treatment decisions

Surveys
A survey and highlights report that summarized trends in pain management for orthopaedic procedures and ailments

Web support
Support of Web-based educational enhancements such as commentaries, pod casts, audio abstracts and video supplements for The Journal of Bone and Joint Surgery Web site

Patient care applications:

EDUCATING RESIDENTS

Journal Clubs
With support from The Journal of Bone and Joint Surgery, journal clubs that encourage orthopaedic residents to appreciate basic and clinical research through regular review, analysis and discussion of recent articles

Symposia
Symposia that help orthopaedic residents sharpen their skills in presenting and defending research proposals

Patient care applications:

FOOT and ANKLE

Matthew B. Dobbs, MD
Localization of the gene that causes club foot deformity, which will result in the development of better treatment strategies

Charles L. Saltzman, MD
Prosthetic ankle joints that function better and last longer, with fewer revisions

John G. Thometz, MD
Evaluation of postsurgical clubfoot patients to determine what optimizes results

Patient care applications:

FRACTURE HEALING

Reginald R. Cooper, MD
Faster and stronger fracture healing with treatments that avoid immobilization, encourage limited movement and accelerate the patient’s return to daily activities

Quanjun (Trey) Cui, MD
Better synthetic grafts to treat nonhealing fractures and other bone defects

James D. Heckman, MD
Use of bone morphogenic protein to repair ununited fractures

Jill A. Helms DDS, PhD
Using genes and associated proteins to help heal difficult fractures

Joseph M. Lane, MD
The development and advancement of the use of Bone Morphogenetic Protein to encourage faster healing of fractures and spinal fusions

Sheldon S. Lin, MD
Demonstration of how effective glucose control can help diabetes mellitus patients' fractures heal faster

Jesse A. Shantz, MD, MBA
Potentially better outcomes, improved pain relief and satisfaction, and lower care costs for upper tibia fracture patients

Patient care applications:

HAND CONDITIONS

Lawrence C. Hurst, MD
New enzyme injection therapies for Dupuytren's disease

L. Andrew Koman, MD
Using sympathectomy to treat Raynaud's disease for patients who have ulcers or do not respond to medication

Zong-Ming Li, PhD
Better strategies for diagnosis, rehabilitation, and treatment of carpal tunnel syndrome

Matthew M. Tomaino, MD
Knowledge of which forces are transferred from hand to elbow, which will mean better treatment for forearm injuries that disrupt stability between the radius and ulna

Patient care applications:

HAND THERAPIES

Richard A. Berger, MD, PhD
Better understanding of the scapholunate ligament, which led to new surgical procedures to heal injured wrists

William P. Cooney III, MD
New resurfacing joints for the hand that are now used worldwide

Kenneth J. Koval, MD
Methods to surgically stabilize distal radius wrist fractures that lead to the best outcomes

Amy L. Ladd, MD
Developing more effective diagnosis and intervention strategies for treating women with thumb carpal metacarpal osteoarthritis

Thomas E. Trumble, MD
Advanced methods for carpal tunnel surgery with less invasive techniques

Scott W. Wolfe, MD
More informed treatment decisions and better surgical techniques, prosthetic devices and rehabilitation methods for patients with wrist injuries

Patient care applications:

HIP CONDITIONS

Young-Jo Kim, MD, PhD
Determination of the point at which using pelvic osteotomy to treat patients with osteoarthritis of the hip ensures the best cartilage repair and joint recovery

James W. Roach, MD
Knowledge of the age at which the results of surgical reduction begin to deteriorate in developmental dysplasia of the hip

Patient care applications:

HIP INJURIES and CARE

Mark A. Asher, MD
Determination that longer bone cement mixing times make it more homogenous and therefore more durable and less likely to crack

Wael K. Barsoum, MD,
Patients receive the treatment—femoral head resurfacing or total arthroplasty—that is most appropriate for their hip, increasing stability of the joint

Benjamin C. Bengs, MD
Pre-operative guidance for surgeons so that patients receive implants that achieve sufficient fixation despite proximal bone loss

James H. Herndon, MD
A life-saving treatment—plugging the femur below a hip prosthesis—to greatly reduce fatalities from fat embolism syndrome

Joshua J. Jacobs, MD
Noninvasive diagnosis of symptomatic total hip and knee replacement prostheses

Harry K. W. Kim, MD
A new means to stimulate healing and improve outcomes for older children and adults suffering from ischemic hip injuries

Marc F. Swiontkowski, MD
Improved hip prosthetics that are less likely to loosen once implanted, helping to reduce postoperative injuries and the need for revision surgeries

Joseph D. Zuckerman, MD
Recognition for research that led to creation of a consensus group that proposed medical, social and governmental interventions for elderly hip fracture patients and recommended education and research to reduce the risk of elderly people breaking their hips

Patient care applications:

INFECTION SOLUTIONS

Catherine G. Ambrose, PhD
Improved treatment for osteomyelitis patients that reduces the risk of unnecessary antimicrobial therapy and development of antibiotic-resistant bacteria

Harlan Amstutz, MD
Reduction of intra-operative infection by using laminar air flow to minimize operating room contaminants

Michael W. Chapman, MD
The use of polymethylmethacrylate-antibiotic combinations to prevent and treat total joint replacement infection

Javad Parvizi, MD
Smart Implants® that will reduce the risk of periprosthetic infection and improve longevity of artificial joints

Robin Patel, MD
Better detection of prosthetic joint infection, allowing for quicker treatment and reduced need for revision surgery

Patient care applications:

INFORMED DECISIONS and QUALITY of CARE

William R. Creevy, MD
Determination of the best, most cost-effective treatments for trauma and other orthopaedic conditions

William B. Macaulay, MD
Considering a patient's lifestyle when deciding whether to treat femoral neck fractures with hemi- or total arthroplasty to ensure the best outcome

Robert G. Marx, MD
Development of a new method for evaluating patient activity levels, allowing for better pain control and quicker recovery

David S. Ruch, MD
Identification of the optimal treatment for common wrist pain, allowing patients to make informed treatment decisions based on effectiveness and risk

Paul M. Saluan, MD
Evaluation instruments that represent an adolescent patient’s perspective and provide clinically relevant information that can inform treatment decisions for upper and lower extremity conditions

James R. Slover, MD
Decreased disparity in orthopaedic treatment for patients of different races, economic strata, and insurance types

Patient care applications:

KNEE INJURIES and TREATMENT

Steven P. Arnoczky, DVM
Replacement of damaged knee cartilage with cadaver cartilage, which may lessen pain and increase mobility

Cristin M. Ferguson, MD
Better scaffolds for meniscus replacement that ensure durability

Donald C. Fithian, MD
Knowledge of which knee injury patients would benefit most from surgical repair

Frank R. Noyes, MD
Treatments that better restore knee stability for patients who have both lower limb malalignment and knee ligament injuries

Mara L. Schenker, MD
Better treatment for meniscus tears that relieves pain, restores function, and slows joint degeneration after injury

Kurt P. Spindler, MD
Longitudinal clinical studies of ACL reconstructions that predict potential failure and that could lead to ways to prevent such failure

Patient care applications:

KNEE REPLACEMENT

Clifford W. Colwell Jr., MD
Determination of what activities and walking aids best help patients with knee implants

Darryl D. D'Lima, MD
Knee prosthetics that can stand up to the stress of daily activity

Stuart Goodman, MD, PhD
New materials for fracture care and joint replacement, resulting in longer lasting prosthetic joints

David C. Markel, MD
Using the knowledge of how inflammatory cells function in both normal and abnormal settings to prevent early implant failure or loosening

Regis J. O'Keefe, MD, PhD
New methods to prevent bone loss around implants

Weiping Ren, MD, PhD
The use of erythromycin to reduce aseptic loosening and the need for revision surgery while increasing implant longevity

Edward M. Schwartz, PhD
Using 3D-CT to measure bone loss and determine if a patient is at high risk of implant failure, allowing for close monitoring and earlier treatment of loosened implants

Nelson F. SooHoo, MD
Standards that could be implemented worldwide to improve  quality and safety of care for joint replacement patients

Shang-You Yang, PhD
Reduced risk of aseptic loosening and methods that prolong the life of a prosthetic joint

Patient care applications:

ONCOLOGY

Matthew J. Allen, PhD
Therapies for metastasizing breast cancer to prevent it from entering and destroying bone

Julia A. Bridge, MD
Knowledge of specific chromosome changes that signal the presence of tumors to help diagnosis and treatment

Steven Gitelis, MD
Better understanding of how chondrosarcoma develops and its associated risks

Hue H. Luu, MD
>Improved diagnosis of which osteosarcoma patients are less likely to develop metastatic disease and can therefore avoid chemotherapy
>Therapies that could reduce the incidence of metastatic disease in osteosarcoma patients

Robert L. Satcher Jr., MD, PhD
Development of new materials that promote bone growth that could reconstitute bone lost after surgery, trauma or cancer

Sean P. Scully, MD, PhD
Better diagnosis of cancerous tumors, resulting in more immediate treatment and a better chance of surviving cancer

Wakenda Tyler, MD, MPH
Treatment methods that improve and extend the lives of patients with renal cell carcinoma

Kristy L. Weber, MD
Targeting the path of metastasizing kidney cancer to prevent it from entering and destroying bone

Patient care applications:

POLICY, PRACTICE and PUBLIC HEALTH

Kevin J. Bozic, MD, MBA
Legislation to improve coding changes to increase reimbursement for total joint revisions

Joseph D. Zuckerman, MD
Recognition for research that led to creation of a consensus group that proposed medical, social and governmental interventions for elderly hip fracture patients and recommended education and research to reduce the risk of elderly people breaking their hips

Patient care applications:

RESEARCH RESULTS—CROSS-SPECIALTY

Harlan Amstutz, MD
Reduction of intra-operative infection by using laminar air flow to minimize operating room contaminants

Mathias P. G. Bostrom, MD
New treatment methods that couple weight-bearing exercise with parathyroid hormone to increase bone mass for better implantation results

Henry J. Mankin, MD
A searchable database that contains the pathology of bone, cartilage, and soft tissue diseases and provides information to make better treatment decisions

Robert G. Marx, MD
Development of a new method for evaluating patient activity levels, allowing for better pain control and quicker recovery

Web support
Support of Web-based educational enhancements such as commentaries, pod casts, audio abstracts and video supplements for The Journal of Bone and Joint Surgery Web site

Patient care applications:

SCOLIOSIS

Philip F. Giampietro, MD, PhD and Cathleen L. Raggio, MD
Identification of risk factors for adolescent idiopathic scoliosis, tailored treatments and the ability to predict how scoliosis patients will respond

Nancy Hadley-Miller MS, MD
Screening for individuals at risk for scoliosis and the development of tailored therapies and counseling to better treat the disease

Stuart L. Weinstein, MD
Compilation of scoliosis data to help surgeons determine the appropriate treatment for scoliosis, decreasing the pain, complications and risks of unnecessary surgery

Patient care applications:

SHOULDER and ELBOW

Brian T. Feeley, MD
Potential treatments that prevent irreversible muscle atrophy after rotator cuff repair

Evan L. Flatow, MD
Comparison of arthroscopic and open rotator cuff repairs, which encouraged further investigations into developing better repair methods to strengthen the tendon and prevent further injury

Mark A. Frankle, MD
Improved understanding of the outcomes of both anatomical and reverse shoulder arthroplasty for the treatment of endstage degenerative shoulder disease

Leesa M. Galatz, MD
Protocols for appropriate strengthening and range of motion exercises to promote better healing after rotator cuff repair

Matthew L. Ramsey, MD
Taking measures with the least associated risks to prevent clots in patients who've undergone shoulder or elbow arthroplasty

Jon K. Sekiya, MD
Zeroing in on when to treat humeral head lesions with allografts to improve shoulder stability after failed standard surgical repair

Stavros Thomopoulos, PhD
Growth factor-based therapies that have the potential to enhance tendon-to-bone healing after rotator cuff repair

Ken Yamaguchi, MD
Establishment of the importance of monitoring tear size in rotator cuff injuries to prevent further damage

Patient care applications:

SPINE

Paul A. Anderson, MD
Use of anterior plate fixation to treat cervical spine fracture patients and lessen their risk of fractures

Henry H. Bohlman, MD
The possibility to recover all or some function after spinal cord injury

Joyce A. DeLeo, PhD
Developing drugs to treat low back pain associated with nerve root injury

Vance O. Gardner, MD
Minimizing ischemic spinal cord injury by developing a cocktail of drugs to prevent cell death

Wellington K. Hsu, MD
Treatment options that could mean better spine fusions and fracture healing for patients who have high levels of dioxin in their systems

Louis G. Jenis, MD
Applying gene therapy to increase patient safety by reducing the amount of BMP needed for difficult spine fusions

Joon Yung Lee, MD
Nonsurgical treatments for patients affected by disc degeneration, which could increase their productivity and reduce the risks and costs of surgical treatment

Paul C. McAfee, MD
Lessened patients' risk of spinal osteoporosis with implants—disk replacements and flexible spinal rods—that preserve spine motion

Sumit H. Rana, MD
Noninvasive injections to treat pain from herniated disks with fewer risks and side effects

Francis H. Shen, MD
> Injections that induce spinal fusion with less risk than traditional grafting
> Bone graft substitutes that could be used for spinal fusions and management of delayed unions, nonunions and treatment of primary fractures

Jeffrey C. Wang, MD
Gene therapy to deliver growth factors for more reliable spinal fusion and a faster recovery

Patient care applications:

SPORTS MEDICINE

Thomas D. Brown, PhD
More effective knee braces for athletes, helping to reduce injuries

William G. Clancy Jr., MD
Patellar tendon grafts that effectively treat anterior and posterior cruciate ligament injuries, allowing patients to return to an active lifestyle.

James R. Slauterbeck, MD
Training programs that teach female athletes how to jump and land in a way that protects their knees and prevents injury

Patient care applications:

TISSUE ENGINEERING

David L. Glaser, MD
Effective stem cell tissue engineering therapies to provide faster healing in common procedures such as rotator cuff repair

MaCalus V. Hogan, MD
Development of tissue engineering therapies to heal, repair and regenerate acute or chronically injured tendons

Mara L. Schenker, MD
Treating meniscus tears with nanofiber implants that relieve pain, restore function and slow joint degeneration after injury

Patient care applications:

TRAUMA

Lee D. Kaplan, MD
Prevention of long-term damage of cartilage after injury, decreasing the risk of further orthopaedic problems

Alfred Kuo, MD, PhD
Tissue regeneration that will improve current surgical procedures to treat cartilage injury

Randall E. Marcus, MD
Better treatments, less pain, and faster healing for patients with long-bone fractures through a new understanding of the metabolic response to traumatic injuries